"Clinical pacemaker standard therapy clinical promotion center" settled in Tiantan Hospital

"Clinical pacemaker standard therapy clinical promotion center" settled in Tiantan Hospital

May 19, 2016 Source: Xinhuanet

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In 2014, Beijing Tiantan Hospital Functional Neurosurgery implanted brain pacemaker (DBS) for the treatment of 500 patients with Parkinson's disease.

At the same time, the nation's first "Clinical Pacemaker Normative Clinical Promotion Center" issued by the National Engineering Laboratory of Neuromodulation Technology was also settled in the Eighth Ward of Tiantan Hospital.

      
Parkinson's disease (PD), also known as tremor paralysis, is one of the most common neurodegenerative diseases. Patients may have motor symptoms or non-motor symptoms such as bradykinesia, myotonia, resting tremor, abnormal posture gait; cognitive/mental abnormalities, sleep disorders, autonomic dysfunction, paresthesia, etc.
        
According to reports, the treatment of Parkinson's disease currently includes two major methods: drug therapy and brain pacemaker surgery. Zhang Jianguo, a professor of functional neurosurgery at Tiantan Hospital, said that brain pacemaker therapy, that is, brain deep electrical stimulation, is performed by implanting electrodes in the brain, sending and discharging pulses to control the relevant nerve nuclei of movement, and regulating abnormal neuroelectric activity. Reduce and control the purpose of Parkinson's symptoms. Brain pacemaker (DBS) is one of the most advanced techniques for the treatment of functional encephalopathy in the international medical community since the 21st century. Among them, treatment with Parkinson's patients is the most common.
        
Cerebral pacemaker therapy for Parkinson's treatment is reversible, adjustable, safe, minimally invasive, etc., can significantly improve the symptoms of patient slowness or imbalance, muscle stiffness and tremor, and can significantly reduce the side effects of taking drugs. The vast majority of patients undergoing brain pacemaker treatment, the overall improvement in motor symptoms, improved quality of life, the ability to return to work, and even participate in physical activity like normal people.
       
Tiantan Hospital Functional Neurosurgery
        
The functional neurosurgery of Beijing Tiantan Hospital was developed under the pioneering, leading and care of the older generation of experts. It has become the key discipline of Tiantan Hospital and a well-known functional disease diagnosis and treatment center in China. The neurosurgical eight-disease functional group was established in the mid-1990s under the leadership of the State's highest science and technology award winner, Wang Zhongxuan, and is a neurosurgical ward that treats functional neurosurgical diseases. Under the advocacy of Academician Wang Zhongcheng, Functional Neurosurgery of Beijing Tiantan Hospital took the lead in developing DBS surgery for dyskinesia in China and achieved success in 1998. Under the leadership of the ward director and doctoral tutor Professor Zhang Jianguo, after many years of hard work, all medical staff have developed the ward into one of the key development disciplines of the national and Tiantan hospitals.
        
Since the establishment of the department, he has accumulated rich clinical experience and has achieved fruitful research results in various fields of functional neurosurgery: the successful application of subthalamic nuclear power stimulation in the world has successfully treated dystonia, Tourette syndrome, Hallervorden- Spatz disease, Fahr syndrome, chorea, etc., since the establishment of the Department, a total of more than 1,000 cases of deep brain stimulation have been completed, reaching the international advanced level, and gained a good academic reputation and social influence, laying a leading position in the country.
        
Functional neurosurgery is an important part of neurosurgery and the fastest growing and most promising sub-discipline; with advanced computer technology, multimodal functional neuroimaging techniques, neuroelectrophysiological techniques and precise stereotactic and navigational techniques The development has made great progress in functional neurosurgery.
        
Help Tsinghua University break the foreign monopoly and open the door to high-end medical treatment for millions of patients
        
The functional neurosurgery of Tiantan Hospital provides a clinical platform to cooperate with Tsinghua University to develop a domestic brain pacemaker. The Tsinghua brain pacemaker products, which are listed in the National Science and Technology Ministry of Science and Technology this decade, are lifting the pain for more patients. Known as a model of translational medicine.
       
The time goes back to November 26, 2009. The first Tsinghua brain pacemaker operation was successfully completed in Beijing Tiantan Hospital, which marked the first time that the brain pacemaker developed in China was implanted in the patient's body. The operation was personally directed by Wang Zhongcheng, the pioneer and founder of the Chinese neurosurgery industry, and Professor Zhang Jianguo completed the procedure. The patient Mr. Zhao is a peasant patient from Hebei. Before the right brain had undergone a destructive operation, after a few years, the left brain had another problem, and the leg was stiff and could not go. "After I have a brain pacemaker, he can run and play. I am very happy to have such an effect. We definitely hope to use domestically produced equipment of high quality and low price, so we are willing to take risks to do trials, clinical, and do The popularization of the treatment will relieve the pain and relieve the burden for the patient as soon as possible.” Professor Zhang Jianguo told reporters that since 2006, he and the Tsinghua Brain Pacemaker R&D team have carried out animal experiments at Tiantan Hospital, and have been monkeys since rabbits and pigs. He said: "In the meantime, we have put forward a lot of suggestions for improvement. They are very open-minded and said that they will change immediately, and they will be changed very timely and in place, so our clinicians are more and more confident about this product."
        
In June 2013, Tsinghua brain pacemaker products went on the market, breaking the monopoly of American companies and making China the second country in the world to master this technology. After the clinical application of Tsinghua brain pacemaker, it will be promoted and applied to more than one year after the end of 2014. More than 50 top three hospitals across the country have carried out more than 1,400 clinical operations.
       
The specialist team creates the world's largest DBS implant center based on the quality and quantity of the surgery
        
Before the listing of Tsinghua brain pacemakers, only one American company's products entered China from around 2000. The price in the Chinese market was about RMB 2,300,000 per 3,000 yuan. The price is difficult for many patients to accept and can only be discouraged.
       
Professor Zhang Jianguo, who witnessed too many patients who were unable to benefit from high-end medical treatment because of the high cost, made him very anxious. At this time, "Tsinghua brain pacemaker broke the exclusive monopoly of the United States" news, at the end of 2013, many Parkinson patients and their families saw hope. "This technological innovation is one of the achievements of China's implementation of the innovation strategy of the medical device industry, and it is the great event that allows science and technology to truly serve the people." Professor Zhang lamented.
        
In order to enable more patients to enjoy the gospel brought by high-tech achievements, the functional neurosurgery of Tiantan Hospital under the leadership of the Beijing Municipal Science and Technology Commission and Tsinghua University jointly promoted the clinical application of Tsinghua brain pacemaker to benefit more patients with Parkinson's disease. The domestically introduced equipment introduced in the hospital is reduced by an average of about 100,000 yuan per imported equipment, which greatly reduces the cost of treatment for patients and reduces the burden on patients. The patients benefited, and thanked the specialist hospitals to reduce the cost of surgery and popularize the technology therapy. At the same time, the number of hospital outpatients surged, and the number of DBS operations in the department reached 500. The functional neurosurgery of Tiantan Hospital has become the largest implant center in the world.
        
In addition, the department has also successfully applied DBS to successfully treat a variety of dyskinetic diseases and mental illnesses, which have reached the international advanced level and obtained good academic reputation and social influence.

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