Myostatin 85 


Myostatin Detail :
Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.

Animals either lacking myostatin or treated with substances that block the activity of myostatin have significantly more muscle mass. Furthermore, individuals who have mutations in both copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy.

Clinical significance:

Mutations
A technique for detecting mutations in myostatin variants has been developed. Mutations that reduce the production of functional myostatin lead to an overgrowth of muscle tissue. Myostatin-related muscle hypertrophy has an incomplete autosomal dominance pattern of inheritance. People with a mutation in both copies of the MSTN gene in each cell (homozygotes) have significantly increased muscle mass and strength. People with a mutation in one copy of the MSTN gene in each cell (heterozygotes) have increased muscle bulk, but to a lesser degree.

In 2004, a German boy was diagnosed with a mutation in both copies of the myostatin-producing gene, making him considerably stronger than his peers. His mother has a mutation in one copy of the gene. An American boy born in 2005 was diagnosed with a clinically similar condition but with a somewhat different cause: his body produces a normal level of functional myostatin; but, because he is stronger and more muscular than most others his age, it is believed that a defect in his myostatin receptors prevents his muscle cells from responding normally to myostatin. He appeared on the television show, World's Strongest Toddler.

Therapeutic potential:

Further research into myostatin and the myostatin gene may lead to therapies for muscular dystrophy. The idea is to introduce substances that block myostatin. A monoclonal antibody specific to myostatin increases muscle mass in mice and monkeys.

A two-week treatment of normal mice with soluble activin type IIB receptor, a molecule that is normally attached to cells and binds to myostatin, leads to a significantly increased muscle mass (up to 60%). It is thought that binding of myostatin to the soluble activin receptor prevents it from interacting with the cell-bound receptors.

It remains unclear as to whether long-term treatment of muscular dystrophy with myostatin inhibitors is beneficial, as the depletion of muscle stem cells could worsen the disease later on. As of 2012, no myostatin-inhibiting drugs for humans are on the market. An antibody genetically engineered to neutralize myostatin, stamulumab, which was under development by pharmaceutical company Wyeth., is no longer under development. Some athletes, eager to get their hands on such drugs, turn to the internet where fake "myostatin blockers" are being sold.
 
Our Lab:


Packaging&Shipping:
1 gram per bottle (plastic bottle or glass bottle) or customized, Protected by bubble film and sealed in a carton/bag.

Hot supply list:
Cosmetic peptides:
1, Matrixyl Acetate (Palmitoyl Pentapeptide)
2, Argireline Acetate (Acetyl Hexapeptide-3)
3, Lipopeptide Acetate
4, SNAP-8 (Acetyl Glutamyl Heptapeptide-3)
5, Dipeptide-2
6 ,Palmitoyl Tripeptide-5(Palmitoyl Oligopeptide)
7, Kollaren/tripeptide-1
8. Matrixyl 3000

Related  products:
 
Packaging & Delivery Process
 
1. With sufficient stock, so we can deliver promptly at the very day upon receipt of the payment.
2. Sophisticated and professional logistic agent. We take responsibility to provide our customers with fast delivery and secure shipping.
3. Well-trained and disciplined packing team. Unique ways to ship 10 grams to 100kg powders at one time to your destination. Fast and discreet shipment could be arranged for customs to pass The Guaranteed. 
4. Packing pictures and tacking code are provided within 12 hours after receiving the payment. Updated tracking information will be provided every other day.
5. After-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved for you immediately.

Our Compeptitive Advantages:

1). Quality guarantee: we are a leading professional factory in China special in pharmaceuticals (featured anesthetics, steriods, and peptides) for more than 14 years. Our product sexported to all over the world.
2). Discreet packing: The best-suited package would be selected to pass customs 100% guaranteed. The package updates would be closely tracked and timely informed. Once any problem found, the package would be reshipped for you.
3). Alternative delivery ways: by land, by air, by sea, by express(FedEx,UPS,DHL,EMS etc.). The most cost-effecient forwarder would be recommanded.
4). Considerate after-service: 24/7 at service for you. Any problem would be valued and solved ASAP.
5). COA (by HPLC) and sample are available at any time.

We know what is important for customers:
- 24 hours customer service
- Discreet packaging
- Fast delivery time
- Quality products
- Best prices
We guarantee you that we meets these points.
Our customers are provided with the best service on internet: every order, big or small, gets personal attention from a highly qualified customer support specialist.
 
Our Popular Peptides :
 
We are the manufacturer of all kinds of hormone powders. We focus on providing customers with high quality products, competitive price, best service and timely delivery. Price: Please let us know the quantity you required, because for small order and bulk purchase, the price will be difference. Payment methods: Western Union, MoneyGram We will supply the receiver's information or the bank account information for payment use. Shipping items: Shipping items will be delivered by international express like EMS, TNT, UPS, FedEx or DHL after receiving received. Every item will be shipped out in 2-3 working days after the payment is done. The product usually arrives in 1-4 days based on the different destination, and online track is provided. Please kindly supply the shipping address, contact and tel number for successful shipment. We are 100% confident of my shipment method, None of our previous packages has ever had any delivery issues.

Popular Steroids Powder and Peptides 



 
 
 

Myostatin 85 


Myostatin Detail :
Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.

Animals either lacking myostatin or treated with substances that block the activity of myostatin have significantly more muscle mass. Furthermore, individuals who have mutations in both copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy.

Clinical significance:

Mutations
A technique for detecting mutations in myostatin variants has been developed. Mutations that reduce the production of functional myostatin lead to an overgrowth of muscle tissue. Myostatin-related muscle hypertrophy has an incomplete autosomal dominance pattern of inheritance. People with a mutation in both copies of the MSTN gene in each cell (homozygotes) have significantly increased muscle mass and strength. People with a mutation in one copy of the MSTN gene in each cell (heterozygotes) have increased muscle bulk, but to a lesser degree.

In 2004, a German boy was diagnosed with a mutation in both copies of the myostatin-producing gene, making him considerably stronger than his peers. His mother has a mutation in one copy of the gene. An American boy born in 2005 was diagnosed with a clinically similar condition but with a somewhat different cause: his body produces a normal level of functional myostatin; but, because he is stronger and more muscular than most others his age, it is believed that a defect in his myostatin receptors prevents his muscle cells from responding normally to myostatin. He appeared on the television show, World's Strongest Toddler.

Therapeutic potential:

Further research into myostatin and the myostatin gene may lead to therapies for muscular dystrophy. The idea is to introduce substances that block myostatin. A monoclonal antibody specific to myostatin increases muscle mass in mice and monkeys.

A two-week treatment of normal mice with soluble activin type IIB receptor, a molecule that is normally attached to cells and binds to myostatin, leads to a significantly increased muscle mass (up to 60%). It is thought that binding of myostatin to the soluble activin receptor prevents it from interacting with the cell-bound receptors.

It remains unclear as to whether long-term treatment of muscular dystrophy with myostatin inhibitors is beneficial, as the depletion of muscle stem cells could worsen the disease later on. As of 2012, no myostatin-inhibiting drugs for humans are on the market. An antibody genetically engineered to neutralize myostatin, stamulumab, which was under development by pharmaceutical company Wyeth., is no longer under development. Some athletes, eager to get their hands on such drugs, turn to the internet where fake "myostatin blockers" are being sold.
 
Our Lab:


Packaging&Shipping:
1 gram per bottle (plastic bottle or glass bottle) or customized, Protected by bubble film and sealed in a carton/bag.

Hot supply list:
Cosmetic peptides:
1, Matrixyl Acetate (Palmitoyl Pentapeptide)
2, Argireline Acetate (Acetyl Hexapeptide-3)
3, Lipopeptide Acetate
4, SNAP-8 (Acetyl Glutamyl Heptapeptide-3)
5, Dipeptide-2
6 ,Palmitoyl Tripeptide-5(Palmitoyl Oligopeptide)
7, Kollaren/tripeptide-1
8. Matrixyl 3000

Related  products:
 
Packaging & Delivery Process
 
1. With sufficient stock, so we can deliver promptly at the very day upon receipt of the payment.
2. Sophisticated and professional logistic agent. We take responsibility to provide our customers with fast delivery and secure shipping.
3. Well-trained and disciplined packing team. Unique ways to ship 10 grams to 100kg powders at one time to your destination. Fast and discreet shipment could be arranged for customs to pass The Guaranteed. 
4. Packing pictures and tacking code are provided within 12 hours after receiving the payment. Updated tracking information will be provided every other day.
5. After-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved for you immediately.

Our Compeptitive Advantages:

1). Quality guarantee: we are a leading professional factory in China special in pharmaceuticals (featured anesthetics, steriods, and peptides) for more than 14 years. Our product sexported to all over the world.
2). Discreet packing: The best-suited package would be selected to pass customs 100% guaranteed. The package updates would be closely tracked and timely informed. Once any problem found, the package would be reshipped for you.
3). Alternative delivery ways: by land, by air, by sea, by express(FedEx,UPS,DHL,EMS etc.). The most cost-effecient forwarder would be recommanded.
4). Considerate after-service: 24/7 at service for you. Any problem would be valued and solved ASAP.
5). COA (by HPLC) and sample are available at any time.

We know what is important for customers:
- 24 hours customer service
- Discreet packaging
- Fast delivery time
- Quality products
- Best prices
We guarantee you that we meets these points.
Our customers are provided with the best service on internet: every order, big or small, gets personal attention from a highly qualified customer support specialist.
 
Our Popular Peptides :
 
We are the manufacturer of all kinds of hormone powders. We focus on providing customers with high quality products, competitive price, best service and timely delivery. Price: Please let us know the quantity you required, because for small order and bulk purchase, the price will be difference. Payment methods: Western Union, MoneyGram We will supply the receiver's information or the bank account information for payment use. Shipping items: Shipping items will be delivered by international express like EMS, TNT, UPS, FedEx or DHL after receiving received. Every item will be shipped out in 2-3 working days after the payment is done. The product usually arrives in 1-4 days based on the different destination, and online track is provided. Please kindly supply the shipping address, contact and tel number for successful shipment. We are 100% confident of my shipment method, None of our previous packages has ever had any delivery issues.

Popular Steroids Powder and Peptides