Scientists in Edinburgh, UK, analyzed nearly 80 depression-related genes by analyzing the British Health Bank’s big data of health. These findings help explain why the disease is at high risk and can also be used to develop drugs for treating mental illness. Related research was published in Nature News.
Depression may be induced by life events, trauma, or stress, but it is not clear why some people are more prone to morbidity than others.
The research team led by the University of Edinburgh analyzed data from the British Biobank, which contains 500,000 people's health and genetic information. They scanned the genetic code of 300,000 people and identified areas of DNA that may be associated with depression.
The study found that some genes that have been precisely located are involved in the function of synapses. These tiny connectors allow brain cells to communicate with each other through electrical and chemical signals. Afterwards, the scientists obtained consent from donors and used 23andMe's personal genetic information data to confirm their conclusions.
Andrew McCann Tosh of the Clinical Brain Science Center at Edinburgh University directed the study. He said: “Depression is a common and serious disease that affects millions of people worldwide. These findings help us to better Learn about its causes, and also show how BBC's Big Data helps promote mental health research.â€
The study's lead author Dr. David Howard, a researcher at the Clinical Brain Science Center at the University of Edinburgh, said the study identified genes that may increase the risk of depression and provided new evidence for the cause. They hope to eventually find effective treatments. (Reporter Fang Linlin)
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