Pharmacological effects
1. Effects on bone marrow hematopoietic system: Rehmannia glutinosa decoction is given to 0.5g of each hemorrhagic anemia mouse, once a day, for 10 consecutive days, can promote the recovery of red blood cells and hemoglobin in anemia animals and speed up the multipotential hematopoietic stem cells ( CFU-S), bone marrow erythroid hematopoietic progenitor cells (CFU-E) proliferation, differentiation.
2. Effects on blood coagulation: Rehmannia glutinosa significantly inhibits hepatic hemorrhagic necrosis and simple necrosis. Hyperlipidemia caused by high-fat foods, fatty liver and hepatic vein hemorrhage caused by endotoxin in rats all have the effect of inhibiting thrombosis. It is thought that the activation of plasminogen is an antithrombotic mechanism of action.
3. Effects on the immune system: The rehmannia alcohol extracts were given to mice by gavage, and the macrophage functions inhibited by carrageenan were obviously protected; and the antibody-producing cells were inhibited.
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4. Effects on the cardiovascular system: Rehmannia glutinosa and steamed rehmannia had significant antihypertensive effects, and systolic blood pressure and diastolic blood pressure were significantly decreased.
5. Anti-oxidize effect.
6. Other effects: The rats were treated with triiodothyronine (T3) to induce yin deficiency model and 3 ml of Rehmannia glutinosa decoction (70% concentration) was given to the stomach for a total of 6 days. The body weight of the hyperthyroid type Yin deficiency rats was changed. The 24-hour drinking water and urine volume, plasma T3, thyroxine (T4) and aldosterone (AD) concentrations were significantly improved, ie, the concentration of T3 decreased, the concentration of T4 increased, and tended to be normal, indicating that Rehmannia glutinosa not only improved Yin deficiency Symptoms and can regulate abnormal thyroid hormone status.
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