What is the difference in efficacy between telmisartan and losartan?

[ China Pharmaceutical Network Health Health ] Both telmisartan and losartan are used to treat essential hypertension, then telmisartan and losartan are two of the most important drugs for sultan antihypertensive drugs. What is the difference in efficacy?

(What is the difference in efficacy between telmisartan and losartan? Image Source: Baidu Pictures)

The application of sartan antihypertensive drugs in hypertensive patients is very extensive. As an angiotensin II receptor antagonist, sartans have many advantages, such as blood pressure reduction without affecting heart rate and blood pressure gradually taking effect. The first dose effect will not occur, even after withdrawal, the efficacy can still last for 2 to 3 weeks and so on. So, what are the differences in efficacy between telmisartan and losartan as the two most important drugs for sultan antihypertensive drugs? Next, this article shared by Xiaobian hopes to bring you some help.

Both telmisartan and losartan are used to treat essential hypertension, while telmisartan is above 55 years of age and is at high risk for serious cardiovascular events and cannot be treated with angiotensin-cyclase inhibitors. Patients, with good results, can effectively reduce the risk of death from myocardial infarction, stroke or cardiovascular disease in these patients. The bioavailability of telmisartan is 50%, while the bioavailability of losartan is relatively low at 33%. In addition, experimental studies by medical personnel have shown that the inhibitory constant of telmisartan is stronger than that of losartan. It is nearly 6 times, so the dose and side effects of telmisartan are also relatively small compared to losartan.

Although losartan may be slightly less effective than telmisartan, according to experts, angiotensin receptor antagonists are the first choice for the treatment of hypertension with diabetes, and losartan has been shown to be strong for 24 hours. It has a high blood pressure, long-term stable blood pressure reduction, improved blood pressure circadian rhythm and cardiovascular and renal protection.

Usually, the side effects of telmisartan common infection symptoms, upper respiratory tract infections including pharyngitis and sinusitis, eczema and arthritis, chest pain are common symptoms; rare anxiety, abnormal vision, dizziness, dry mouth, flatulence, sweating and so on. The side effects of losartan are mainly abdominal pain, fatigue, heart palpitations, edema, diarrhea, nausea, indigestion, dizziness, headache, insomnia, cough, nasal congestion, pharyngitis and upper respiratory tract diseases.

The above is all the content I shared today. I want to get more free friends with high blood pressure, coronary heart disease drugs, medical care and health knowledge. We can search for "Good Heart Shu Guan Xin Zhi Guan Jia" and pay attention to it. We welcome you to WeChat for chronic disease. Thank you. your attention. If you feel that something is wrong with this article, you are welcome to point out in the comments section that your suggestion is the biggest motivation for our progress. You can also send the high blood pressure problems you care about in the comment area, and the small series will be integrated and shared, and look forward to your comments and comments! All the information related to medication, symptoms and other commonalities are more, and the personality is less. The readers and friends should take all the guidance of professional doctors as the standard, and do not use drugs at will.