Chinese scientists have developed a genetic editing "safety scissors" aimed at conquering rare diseases
June 13, 2019 Source: Xinhua News Agency
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Xinhua News Agency, Shanghai, June 12 (Reporter Wang Linlin) Gene editing technology known as "magical scissors" is regarded as a weapon to overcome human terminal illness. On the 10th, the international academic journal "Nature" published the latest achievements of Chinese scientists online. The Yang Hui team of the Center for Brain Intelligence of the Chinese Academy of Sciences and its collaborators developed a "safety scissors" with more accurate editing effect - ABE (F148A), shortened The clinical trial time to overcome rare diseases.
The team first thoroughly tested a variety of genetic editing “scissors†that are currently used in academic research and clinical practice. They recently discovered that the existing “scissors†not only have the risk of cutting “mistakes†but also destroy a large amount of ribonucleic acid ( RNA), which has a high risk of cancer.
There are more than 7,000 rare diseases known to humans, hundreds of millions of people worldwide, and about 95% of rare diseases have no effective treatment, once they get sick. The scientific community is trying to solve the rare disease problem with gene editing technology. "In theory, the use of gene editing technology can make patients regain health. But because the safety of cutting can not be guaranteed, there are only a few genetic editing 'scissors' in the world to start clinical trials." Yang Hui said.
To significantly reduce the turnover rate of the gene "scissors" without destroying the ribonucleic acid, the team developed a "safety scissors" - ABE (F148A). The results show that the "safety scissors" can not only cut more accurately. Genes, and will not "injure" the ribonucleic acid, the risk of cancer is greatly reduced.
Industry experts believe that the gene editing "scissors" are safer and are expected to be pushed to the clinic more quickly. The first step can be used to treat rare diseases such as thalassemia, macular degeneration, hereditary deafness, etc. Gradually used in the treatment of common diseases, such as cardiovascular diseases, neurodegenerative diseases and the like.
The reporter was informed that the results have now completed the patent application, and is transforming into clinical and industrial through the establishment of animal model production platform, gene editing and treatment strategy research and development platform, clinical trial and effect evaluation platform.
Related paper information: https://doi.org/10.1038/s41586-019-1314-0
Children's masks, medical surgical disposable children's medical masks, three-layer masks, unique packaging for girls and boys, and for children. Buy masks, certify us, and guarantee authenticity. Three-layer filtration, medical quality. Three-dimensional protection, multi-layer filtration, medical quality, breathable and skin-friendly. Plastic nose clip. The outer non-woven fabric blocks droplets, dust, etc., so that every breath of the child is more at ease. Intermediate filter cloth, flannel cloth filter particles, bacteria, etc. The inner non-woven fabric is skin-friendly, comfortable and more breathable.
China Kids Nonwoven Mask,Protective Disposable Face Mask manufacturers, welcome Anti Dust Activated Disposable Face Mask,Protective Children Face Mask purchasers from worldwide to visit our site.
Kids Nonwoven Mask,Protective Disposable Face Mask,Anti Dust Activated Disposable Face Mask,Protective Children Face Mask
KUTA TECHNOLOGY INDUSTRY CO.,LIMITED , https://www.kutasureblue.com