Jinbao gives you an analysis of the reasons why pig diseases are difficult to treat!

Abstract: The majority of farmers in the pig breeding industry are not difficult to find that the current pig diseases are becoming more and more difficult to cure. Even sometimes we spend a lot of money and manpower to suppress the death of pigs and bring greater economic losses. Why is it more and more difficult to cure pig diseases?

There are many reasons for this, and the following points are summarized:

1. The cause of the pathogen

There is no doubt that no pathogenic microorganisms will have no disease. The pathogenic microorganisms are easy to deal with and there is no problem of prevention and control. Disease prevention and control are closely related to the characteristics of pathogens, mainly in the following areas.

The biggest obstacle to the health of herds is the primary viral infection.

Viral infections (including latent infections) are almost a regular problem with bacterial infections. Clinical veterinary medicine generally only pays attention to the treatment of the card, but often similar symptoms occur after stopping the medicine. As long as the virus infection is not resolved, bacterial infection problems will recur.

Viruses that are infected in the animal's body can hardly be killed by any drug. Instead, they can only be eliminated by the animal's own immune cells, subcellular components and their secretions.

Viral variation is a common practice in the biological world.

There are different genotypes or serotypes in the same virus, and there is almost no interactive immunity between strains, such as PRRSV and foot-and-mouth disease.

At present, many viruses commonly infected by swine, such as pseudorabies virus, circovirus, and "blue ear disease" virus, are viruses that severely destroy the function of the animal's immune system.


2. The reasons for the pig body

From the philosophical point of view of biological evolution, there is a powerful barrier called "immune" in the pig's body to fight pathogenic microorganisms. However, slenderness is one of the characteristics of immunity. Immunity is not so stable from beginning to end.

There are many factors that lead to poor immunity of swine. To sum up, there are mainly the following aspects:

Physicochemical factors: mycotoxins in feed (such as aflatoxin B1, ochratocin, etc.), heavy metals (such as mercury, lead, etc.), industrial chemicals (such as excessive fluoride), and endotoxins produced by metabolic disorders Can both poison and interfere with the normal physiological function of the body's immune system. A large number of radiation-emitting animals (such as long-term ultraviolet light irradiation) can kill bone marrow stem cells and destroy their bone marrow function, resulting in serious damage to hematopoietic stem cells and cause loss of hematopoietic function and immune function.

Pharmacological factors: Some drugs (such as dexamethasone and other glucocorticoids, chloramphenicol, tetracycline, etc.) can suppress the immune system even at the therapeutic level. Long-term and large-scale use of antibiotic antibiotics can inactivate immune activity. Destroy the body's balance and impair immunity.

Nutritional factors: The relationship between nutrition and immunity is intricate and intricate. Excessive or lack of certain nutrient elements, whether basic nutrients, or essential nutrients or even trace amounts of nutrients, directly or indirectly cause damage to the animal's immune and immune organs.

Bad stress: It has been proved that under stress conditions such as overcooling, overheating, congestion, delivery, weaning, mixed groups, and transportation, abnormal metabolites such as hot emergency proteins are produced in livestock and poultry, and levels of certain hormones (such as steroids) are also It will greatly increase, they will affect the activity of lymphocytes and cause significant immunosuppression.

Infectious immunosuppressive diseases: Many pathogenic microorganisms can induce significant immunosuppression in the body. Such as swine fever virus, porcine reproductive-respiratory syndrome virus, Mycoplasma hyopneumoniae and so on.

Early Weaning Techniques: Piglets are born by eating breast milk to obtain immunoglobulins that are resistant to pathogenic microorganisms. With the increase of age, pigs gradually improve their own immune system, accurately speaking, 70 days after the piglets can improve their immune function, that is, the body can effectively protect themselves against the invasion of pathogenic microorganisms. However, the early weaning technique was based on the fact that the active immunization of the piglet itself had not yet been established, but the passive immunization of the maternal antibody abruptly stopped and the piglet body was undergoing an immune blanking period, which was about 4 weeks. At this time, the piglets are in a state of high stress both inside and outside, namely, environmental stress, nutritional maladjustment, mental heart attack and physical development are not perfect, mainly due to lack of immunity, so the 35-70-day-old piglets are the most vulnerable All kinds of pathogenic microorganisms take advantage of the fact that they often multiply in bacteria and cause the body to become ill.

Facts have proven that the various factors that cause the disease are not isolated. She often promotes each other and causes and causes each other, which makes the etiology of various diseases become very complicated. This is also the current difficulty in diagnosis and prevention of swine diseases in swine production. The root cause lies. Therefore, in order to solve the problem of difficult disease prevention and control, we must adopt comprehensive prevention and control measures: to strengthen the feeding and management of pigs, and to rationally use drugs and vaccines on the basis of controlling the ingestion safety of pigs and the comfortable and comfortable living environment.

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