Successful development of new blood pressure lowering nano drugs
January 15, 2019 Source: Science and Technology Daily
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];The National University of Novosibirsk, Russia, developed a special nanoparticle that lowers blood pressure and tested it in mice with high blood pressure. The research results were published in the Journal of Hypertension.
The university biologist Asya Levina said: "Our drugs are a complex of nanoparticles and short DNA molecules. Nanoparticles help DNA molecules enter cells, bind to messenger RNA, prevent protein formation, and therefore, cells The number of receptors in the test will not increase and blood pressure will not rise."
The researchers tested the drugs on mice that were prone to extremely high blood pressure in times of stress. The results of the experiment showed that the low-dose nanoparticles reduced the blood pressure of the mice by about 10-12 mm Hg, and the effect of one intake lasted for nearly one week. In addition, the researchers emphasized that the animals did not feel any discomfort during the experiment and did not suffer from the side effects of ingesting large amounts of the drug.
Vitamins are a type of trace organic substances that humans and animals must obtain from food in order to maintain normal physiological functions. In terms of physiological functions, vitamins are neither a raw material for tissues nor a substance for supplying energy, but they are an indispensable substance for the body. It has many types and different chemical structures. Most of them are the components of the coenzyme (or prosthetic group) of certain enzymes. They are the indispensable compounds for maintaining the normal growth (growth, health, reproduction and production function) of the body. It plays a catalytic role in the body to promote the synthesis and degradation of major nutrients (proteins, fats, carbohydrates, etc.), thereby controlling metabolism. Vitamins are essentially low-molecular organic compounds. They cannot be synthesized in the body, or the amount synthesized is difficult to meet the needs of the body, so they must be supplied from the outside. The daily requirement of vitamins is very small (usually measured in milligrams or micrograms). They are neither a raw material for body tissues nor a substance for energy supply in the body. However, they do not regulate material metabolism, promote growth and development, and maintain physiological functions.
Vitamin K2 MK-7, Vitamin C, Vitamin E, Vitamin K2, Vitamin H, Vitamin D3
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