Ars Technica, a US technology media, recently announced a major advance in the vaccine industry: the National Institutes of Health (NIH) announced the launch of a Phase I clinical trial of a vaccine against all mosquito-borne diseases. The vaccine, called AGS-v, targets the saliva of mosquitoes rather than individual germs.
The "threat" of mosquitoes to humans goes far beyond the snoring of the ear and the itchy bags left on the skin. They carry and spread various pathogens, such as the Zika epidemic of large-scale outbreaks, as well as dengue fever, malaria, and yellow. Fever and so on. By biting humans, mosquitoes infect hundreds of millions of people every year. Only dengue fever, which infects about 390 million people in a year, and the number of malaria infections is as high as 214 million per year. Scientists have been hoping for a vaccine to fight all of these infections, and the UK's Sik Biotech Group and NIH are pushing this dream into reality.
After a decade of exploration, the Sicco Group developed the AGS-v vaccine, which allows humans to be immune to all diseases transmitted by mosquitoes. The company believes that the vaccine is equivalent to a "weapon", and if the mosquito bites the person who vaccinates the vaccine, it will face the "end" of death or inability to reproduce. AGS-v is not a vaccine that is usually vaccinated to prevent a specific disease. Instead, it creates a "sentinel" for the mosquito saliva in the human body, an immune system. When mosquitoes leave saliva in the body, the immune system produces an allergic reaction that “kills†the pathogens that enter the body.
The idea of ​​scientists targeting mosquito saliva has been around for a while. The mosquito saliva contains a variety of proteins. The new vaccine was developed using four proteins that are usually found in mosquitoes, but currently, it has not been shown. Data on the safety and efficacy of vaccines.
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