Radix Isatidis (commonly used as an alias: Amaranthus glabra, Radix Astragali, Radix Astragali) is a traditional Chinese medicinal material. It is produced all over China. Banlangen is divided into the north Banlangen and the southern Banlangen. The origin of the northern Banlangen is the roots of the cruciferous plants Isatis tinctoria L. and I. indigotica Fort. The southern Banlangen is the Bacillus plantae Baphicacanthus. Roots and roots of cusia (Nees) Brem.). With Qingrejiedu, cooling blood swelling, Liyan effect.
Pharmacological effects
1. Antibacterial and antiviral effects:
Indigo root has effects on various bacteria. Aqueous extracts have inhibitory effects on Bacillus subtilis, Staphylococcus aureus, Staphylococcus aureus, Escherichia coli, Salmonella typhi, Paratyphoid fever parasites, dysentery (Shiga, Freund's), enterobacteriaceae, etc.; acetone extracts are also similar Effect, and effective for hemolytic streptococcus (all agar plate method). The antibacterial effect on meningococcal group A was similar to garlic and honeysuckle. The antibacterial and antiviral active ingredients of Radix Isatidis and Folium Isatidis are thought to be aphid. Experiments have shown that earthworms have no antibacterial effect in vivo and in vitro; the antiviral effect in vitro is not prominent; and excretion in the body is fast, so it is considered that it has no obvious physiological and antibacterial activity. Its active ingredients are yet to be studied.
2. Anti-leptospirosis:
Radix Isatidis or Folium Isatidis higher than 1:100 has the role of killing the endogenous spirochetes in the trial.
3. Detoxification:
According to reports, dogs with Radix Isatidis, Coptis flour and Veratrum powder served in the same (2.0g/kg each), can solve the worm poison, reduce mortality; if veratrum poisoning after use, it is invalid; Radix isatidis or Coptis powder is not effective.
4. Improve immune function:
Intraperitoneal injection of Radix Isatidis polysaccharide 50 mg/kg significantly promoted the immune function in mice, which showed that it could significantly increase the spleen weight of normal mice. The total number of white blood cells and lymphocyte counts significantly inhibited the decrease of spleen index, the total number of white blood cells, and the number of lymphocytes in mice with immunosuppression caused by hydrocortisone; significantly increased normal and cyclophosphamide induced by dinitrochlorobenzene. Delayed hypersensitivity reaction induced by immunosuppressive mice; Increased percentage of ANAE-positive lymphocytes in peripheral blood of normal mice and apparently counteracted the immunosuppressive effects caused by hydrocortisone; but in vitro experiments with Isatis root polysaccharides induced by Concanavalin A No significant enhancement of the lymphocyte reaction was observed in spleen cells of mice. In addition, Radix isatidis polysaccharide can significantly enhance the function of antibody-forming cells and increase the rate of carbon particle clearance for intravenous injection in mice.
5. Anti-tumor effect:
For the rat W256 solid tumor and mouse Lewis lung cancer injection of Indirubin 200 mg/kg for 6-7 consecutive days, the inhibition rate of rat W256 solid tumor was 47-50% and 50-58%, respectively. Reduced to less than 100mg/kg daily, the inhibitory effect is not obvious. Indirubin 500mg/kg gavage, the inhibition of W256 solid tumor in rats was 23-33%, the inhibition rate of mouse sarcoma 180 is about 30%. Indirubin can prolong the survival time of lymphoblastic leukemia L7212 mice by 20%. In addition, the mouse spermatogonia test showed that indirubin can not specifically inhibit the type B spermatogonia and sperm cells.
6. Effect on leukemia:
Preliminary pharmacological studies have shown that indirubin has a role in the destruction of leukemia cells. From the ultrastructural morphology, under the effect of Indirubin, degenerated and necrotic cells are mostly swollen and soluble necrotic. It was found that indirubin can enhance the phagocytic activity of the mononuclear macrophage system in animals. The mononuclear macrophage system plays a role in the body's immune response, so the anti-cancer effect of indirubin may be related to improving the body's immunity.
Radix is ​​bitterly cold, with heart, stomach, liver, and gall bladder. Function Qingrejiedu, cooling blood and pharynx. Attending temperature-induced diseases, such as flu, upper respiratory tract inflammation, meningitis, mumps, acute enteritis, dysentery, hepatitis, facial erysipelas, fever spots and so on. Although pharmacological studies have shown that Banlangen has a significant inhibitory effect on many viruses and germs, don't forget that it is a bittersweet drug. Therefore, the above diseases can only be used when there are symptoms of warmth, heat toxicity, and damp heat.
1, Indigo radical treatment of influenza: Banlangen 50 grams, not live 25 grams. Jiantang, the second day of service, and even served two to three days. ("Jiangsu Recipe Herbal Selection")
2. Indigo Radix is ​​used to cure the brain: Banlangen, Daqingye decoction has a strong killing effect on meningococcus. With Daqingye, Banlangen 25 grams, 15 grams of licorice, Jianshui drink, and even served 3 to 5 days, the brain has a good preventive effect.
3, Indomethacin cure big head days, begin to feel cold body weight, sub-massage head swollen, head can not be opened, on the asthma, bad throat, thirsty tongue dryness: Astragalus (wine fried), Coptis (wine fried) 25 grams, orange peel (to white), licorice (raw), Scrophulariaceae 10 grams, Forsythia, Banlangen, Puffballs, rat aphids, mint 5 grams, 3.5 grams of silkworm, Cimicifuga, Bupleurum, Campanulaceae 10 grams. For the last soup, always serve, or honey mixed for the pill, dip. (Li Wei, Puji Disinfection Drink)
4, Banlan radical cure red eye disease: Banlangen 30 grams, 9 grams of dandelion, raw licorice 6 grams, add Shuijianbi, can prevent red eye disease. 9 grams of dandelion, 6 grams of wild chrysanthemum, Radix 9 grams, 3 grams of Coptis, Jianshui, fumigation, 3 to 4 times a day, excellent for the treatment of fulminant pink eye.
5, Banlangen prevention of epidemic parotitis: Banlangen, Mountain mushroom each 50 grams, 40 grams of Forsythia, licorice 30 grams, 5 grams of barley (blunt). The medicine is soaked in water for half an hour, put into a large casserole, put 800 to 1000 ml of fresh water, and simmered into 500 ml, divided into 10 portions and put into a vial.
6, Banlan radical cure viral hepatitis: During the epidemic, capillaris, Banlangen, Guanzhong each 15 grams, Shuijianbi, twice daily, prevention and treatment.
7, Indigo radical cure hepatitis: Banlangen 50 grams. Shuijianbi. ("Liaoning Common Chinese Herbal Medicine Handbook")
8, Banlan radical mumps: Banlangen 30 grams, Jianshui taking, and even served 5 days, there is a certain degree of prevention. Mumps fever, swelling and pain can be used Banlangen 30 grams, 15 grams of wild chrysanthemum, Yinhua 10 grams, Jianshui drink, have a good therapeutic effect. Radix isatidis 30g, Guanzhong 15g, licorice 3g, Shuijianbi, 1 day, even for 5 days, and those who have close contact with mumps can prevent infection.
9, indigo radical cure pox out of time: Banlangen 50 grams, 1.5 grams of licorice (pan, fried). The same as for the fine, each serving 2.5 grams or 5 grams, take the rooster blood three or two points, with a little warm wine, after eating, under the same tone. ("Ran's Pediatric Party Theory")
Medication taboo
Those who are physically insane but do not have fiery poison are afraid of serving Banlangen.
Deficiency of physical fitness, frequent colds, chronic gastroenteritis, hypotension, lack of energy, people with allergies, diseases of the blood system, other diseases such as gastroptosis, peptic ulcer, hypothyroidism, arrhythmia, etc. Also use Banlangen with caution.
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