White blood cells will always tear holes in your blood vessel wall. But these immune system guards do this to protect you: if they need to travel through the bloodstream to the infected tissue (where they make antibodies and swallow foreign invaders), they first need access to the internal channels of the blood vessels.
Now, scientists have discovered how they can do this without permanently damaging the blood vessels because they drill into the wall of the blood vessel more than 10 times a day.
First, researchers added fluorescent markers to their nucleus and vascular wall structural fibers, which block foreign particles and seal blood, plasma, and immune cells. The researchers followed up the process with a video microscope. They found that vascular cells were not previously thought to cut small cells. Instead, immune cells pass through the walls of the blood vessels.
By softening its larger nuclei and pushing them to the cell front, white blood cells can separate the transitional stent in the vessel wall with a probe and then squeeze it into the interior, the researchers published online in the Cell Report on January 17th. This achievement is reported in the paper.
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