Two "like blastocysts"
Image source: "Nature" magazine official website
On May 3, a team of European scientists published a medical paper in the British journal Nature on the 3rd, saying that they only used mouse stem cells to cultivate a structure similar to that of early embryos in a culture dish. It provides researchers with a cell culture model for early development that helps illuminate the key processes that underpin this important life stage.
Mammalian fertilized eggs are divided into many small cells by cleavage, and the hollow spheres composed of these small cells are called blastocysts. In fact, at this stage of blastocyst, all cells did not begin to differentiate, and then the embryo began to differentiate. The globular structure of the blastocyst is composed of a trophoblast, an inner cell mass and a liquid-filled blastocyst cavity, which contains a large number of embryonic cells.
Stem cell lines have been taken from trophoblasts and embryonic cells. This time, Nicholas Lifron and colleagues at the Maastricht University in the Netherlands and the Institute of Stem Cell and Developmental Biology at the Royal Netherlands Academy of Sciences and colleagues have shown that these two types of cells can interact in vitro to form blastocysts. The structure they call it a "blastoid".
This "like blastocyst" is shaped like a 3.5-day blastocyst and exhibits a similar pattern of gene activity. Like blastocysts, "cytoplasmic blastocysts" form when internal stem cells signal to induce trophoblast development. During normal development, the trophoblasts continue to form the placenta, so the researchers hope that their models will help people understand how the placenta is formed and how the embryos are implanted into the endometrium.
Research on embryonic stem cells has long been in a controversial situation. After the transfer of these early embryo-like structures into the uterus, the spherical structure triggers a remodeling event similar to that that occurs when implanted in the uterine wall. They do not develop into mature embryos, but they still provide a scientific cell culture model for early development in today's scientific community, helping to elucidate the key processes that underpin this important life stage.
Editor-in-chief
The current significance of artificial "embryos" is that it makes it easier and convenient for scientists to study the origin of human life, and it is also helpful to explore the entire growth process of life. However, in culture dishes, the creation of embryo-like structures from stem cells alone does provide a whole new way to create life. Therefore, as technology matures, it will certainly trigger a new round of bioethical debate.
We're professional Arthroscopy Instruments manufacturers and suppliers in China, specialized in providing high quality medical instruments with reasonable price. We warmly welcome you to buy or wholesale bulk Arthroscopy Instruments for sale here and get quotation from our factory.
Arthroscopy Set,Orthopedics Forceps,Arthroscopy Instruments,Arthroscopic Instruments Set
Tonglu WANHE Medical Instrument Co., Ltd , https://www.vanhurhealth.com