Release date: 2018-05-03
Taiwan's "Academia Sinica" biomedical research institute released the latest research results on the 2nd, saying that the over-expressed oncogene paraspeckle Component 1 (PSPC1) in cancer cells promotes proliferation, invasion and metastasis of cancer cells. If the future can inhibit the performance of this gene, it will reduce the growth and spread of cancer cells and help develop new cancer drugs. It is reported that related research papers have been published in the journal Nature Cell Biology.
The reporter learned from the press conference held by the "Academia Sinica" on the same day that one of the main causes of death of cancer patients is the invasion and metastasis of cancerous tumor cells. Previous studies have found that the transmission of transforming growth factor-β1 (TGF-β1) Play an important role in the mechanism of cancer metastasis. However, because this factor can inhibit normal cell proliferation and promote cancer cell proliferation, invasion and metastasis, the scientific community is not clear about its role in different stages of cancer.
In order to find out the key factors of cell cancer, the relevant research team of the organization uses whole-genome analysis of malignant tumors such as lung cancer, breast cancer, liver cancer and prostate cancer, and finds that there are genetic variants in the tumor tissue, and abnormal performance is related to the survival rate of patients. Gene.
Source: Xinhua News Agency
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